Spravato treatment planning for depression that has not improved enough.
Synergy Mind & Wellness PLLC provides Spravato education, esketamine treatment consultation, ketamine therapy discussion, safety screening, and advanced depression treatment planning for eligible patients. Treatment decisions are based on diagnosis, prior response, medical history, medication profile, safety factors, and clinical appropriateness.
A structured option for eligible patients.
Spravato-related care requires screening, education, monitoring, transportation planning, and close follow-up.
Watch a quick overview of Spravato treatment.
This educational video provides an overview of Spravato/esketamine treatment and may help patients understand why monitoring, safety screening, and treatment planning matter before starting care.
Esketamine nasal spray administered under medical supervision.
Spravato is esketamine nasal spray. Unlike a typical take-home prescription, Spravato is administered in a certified healthcare setting. Patients are monitored after dosing because sedation, dissociation, blood pressure changes, and other safety considerations can occur.
Nasal spray treatment
Spravato is administered as an intranasal esketamine treatment under direct supervision in an appropriate clinical setting.
Observed treatment session
Patients remain in the clinic for monitoring after administration and must be clinically stable before leaving.
Transportation planning
Patients should not drive after treatment and need a safe transportation plan for each treatment session.
For eligible adults with depression that needs a more advanced treatment review.
Spravato is not the right treatment for every patient. A consultation reviews your symptoms, diagnosis, prior medication trials, medical history, blood pressure risks, substance use history, current medications, transportation plan, and ability to complete required monitoring.
- Depression symptoms that have not adequately improved with standard treatment
- History of medication trials with limited response or tolerability concerns
- Need for advanced treatment planning beyond routine medication changes
- Ability to attend monitored sessions and arrange transportation afterward
- Appropriate safety profile after medical and psychiatric screening
What a Spravato care pathway may include.
The goal of consultation is to determine whether Spravato, ketamine-related referral, TMS, medication optimization, therapy, or another treatment path is most appropriate. Safety and monitoring requirements are central to this decision.
- Diagnosis review: confirm symptoms, depression history, prior diagnoses, and treatment response.
- Medication review: assess antidepressants, psychiatric medications, medical medications, and safety considerations.
- Medical screening: review blood pressure, cardiovascular history, neurologic history, and contraindication concerns.
- REMS education: explain supervised dosing, monitoring, transportation, and clinic requirements.
- Care plan: determine whether Spravato, TMS, medication changes, therapy, referral, or higher-level care is appropriate.
Spravato requires structured post-dose observation.
After Spravato administration, patients are monitored for clinical stability before leaving the treatment setting. Common safety topics include sedation, dissociation, blood pressure changes, nausea, dizziness, and impaired ability to drive.
- Blood pressure and clinical status monitoring
- Observation for sedation, dissociation, dizziness, or nausea
- No driving or operating machinery until the next day after restful sleep
- Transportation planning for every treatment session
- Follow-up review of symptom response, side effects, and safety
Common questions before booking.
What is Spravato?
Spravato is the brand name for esketamine nasal spray. It is administered under supervision in a certified healthcare setting with monitoring after each dose.
Is Spravato the same as ketamine infusion therapy?
No. Spravato is esketamine nasal spray. Ketamine infusion or injection therapy uses ketamine through a different route and is a different treatment pathway. A consultation can help clarify which option may be appropriate.
Do I take Spravato home?
No. Spravato is not taken home like a routine prescription. It is administered in a certified healthcare setting with required monitoring after treatment.
How long do I need to be monitored?
Monitoring requirements depend on the treatment protocol and patient status, but Spravato treatment requires post-dose observation before the patient is released from the healthcare setting.
Can I drive after Spravato?
No. Patients should not drive or operate machinery until the next day after restful sleep. A transportation plan is required for each treatment session.
Can Spravato replace emergency care?
No. Spravato is not emergency care. If you are in immediate danger, having thoughts of harming yourself or someone else, or experiencing a medical or psychiatric emergency, call 911, go to the nearest emergency room, or call/text 988.
Interested in Spravato or advanced depression treatment options?
Book a consultation with Synergy Mind & Wellness PLLC to review your symptoms, treatment history, safety factors, and whether Spravato, TMS, medication optimization, therapy, or another pathway may be appropriate.
Spravato/esketamine treatment, ketamine-related referrals, TMS, medication management, and other treatment options depend on diagnosis, eligibility, safety screening, provider judgment, availability, and applicable regulations. If this is an emergency, call 911. For emotional distress or suicidal crisis, call or text 988.

